Elimination of alpha-gal xenoreactive epitope: alpha-galactosidase treatment of porcine heart valves.

Abstract

BACKGROUND AND AIM OF THE STUDY Porcine heart valves are among the most widely used tissue valves in clinical heart valve implantation. However, immunologic responses have been implicated as potential causes of the limited durability of xenograft heart valves. The study aim was to determine the effectiveness of alpha-galactosidase treatment used to degrade… (More)

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