Elimination and biochemical responses to intravenous alendronate in postmenopausal osteoporosis.

Abstract

Postmenopausal women with established vertebral osteoporosis were studied for 2 years to determine the terminal elimination half-life and the duration of response to treatment with intravenous alendronate (30 mg) given over 4 days. The urinary excretion of alendronate followed a multiexponential decline. Approximately 50% of the total dose was excreted over… (More)

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Cite this paper

@article{Khan1997EliminationAB, title={Elimination and biochemical responses to intravenous alendronate in postmenopausal osteoporosis.}, author={S. A. Khan and J. A. Kanis and Samuel D Vasikaran and Walter F Kline and Bohdan Matuszewski and E. V. Mccloskey and Monique Ben{\'e}ton and Beate Gertz and David G Sciberras and S. D. Holland and Jane M. Orgee and Gillian Coombes and Simon Rogers and Annaliza Porras}, journal={Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research}, year={1997}, volume={12 10}, pages={1700-7} }