Eliminating carcinogenic acetaldehyde by cysteine from saliva during smoking.

  title={Eliminating carcinogenic acetaldehyde by cysteine from saliva during smoking.},
  author={Ville J Salaspuro and Jaana M Hietala and Martti L. A. Marvola and Mikko P Salaspuro},
  journal={Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology},
  volume={15 1},
Tobacco smoking is one of the strongest risk factors not only for lung cancer but also for cancers of the upper gastrointestinal tract. Acetaldehyde has been shown to dissolve into the saliva during smoking and to be a local carcinogen in the human upper digestive tract. Cysteine can bind to acetaldehyde and eliminate its toxicity. We developed a tablet that releases cysteine into the oral cavity during smoking and could therefore be a potential chemopreventive agent against toxicity of tobacco… CONTINUE READING


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