Elicitation of intraspecific defence reactions in the rat from midbrain periaqueductal grey by microinjection of kainic acid, without neurotoxic effects.


Microinjection of 40 pmol of the neuroexcitotoxin, kainic acid (KA) in the midbrain periaqueductal grey region (PAG) evoked a significant increase in both defensive and immobile behaviours in rats tested in a social situation. The evoked reactions appeared identical to the rat's natural defensive reaction to attack by a conspecific, although they were… (More)