Elicitation of Taxus sp. cell cultures for production of taxol

@article{Ciddi2004ElicitationOT,
  title={Elicitation of Taxus sp. cell cultures for production of taxol},
  author={Veeresham Ciddi and Venkatesh Srinivasan and Michael L. Shuler},
  journal={Biotechnology Letters},
  year={2004},
  volume={17},
  pages={1343-1346}
}
SummaryThe addition of cell extracts and cultures filtrate of Pencillium minioluteum, Botrytis cinerea, Verticillium dahliae, and Gilocladium deliqucescens on the tenth day after transferring Taxus sp. (RO1-M28) cell suspensions into an induction medium, further improved the production of TaxolTaxol is a registered trademark of Bristol Myers Squibb for paclitaxel. and total taxanes. Arachidonic acid (1mg/L) addition at the time of inoculation increased Taxol production by 150%. Oxidative stress… 
Plant cell culture for production of paclitaxel and other taxanes.
  • J. Zhong
  • Biology, Engineering
    Journal of bioscience and bioengineering
  • 2002
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Involvement of NO in fungal elicitor-induced activation of PAL and stimulation of taxol synthesis inTaxus chinensis suspension cells
TLDR
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Oxidative Stress and Taxol Production Induced by Fungal Elicitor in Cell Suspension Cultures of Taxus Chinensis
TLDR
It is concluded that oxidative stress had the deleterious effect onTaxus chinensis cell suspension cultures with fungal elicitor and ascorbic acid changed the oxidative stress and taxol production.
Production of Taxol and its Analogues from Cell Cultures of Taxus wallichiana
TLDR
Preursors and growth retardants significantly improved the production of taxol, DAB and BA in cultures grown in production medium and on HPLC analysis using photodiode array detector.
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