Elicitation of Taxus sp. cell cultures for production of taxol

@article{Ciddi2004ElicitationOT,
  title={Elicitation of Taxus sp. cell cultures for production of taxol},
  author={V. Ciddi and V. Srinivasan and M. Shuler},
  journal={Biotechnology Letters},
  year={2004},
  volume={17},
  pages={1343-1346}
}
  • V. Ciddi, V. Srinivasan, M. Shuler
  • Published 2004
  • Biology
  • Biotechnology Letters
  • SummaryThe addition of cell extracts and cultures filtrate of Pencillium minioluteum, Botrytis cinerea, Verticillium dahliae, and Gilocladium deliqucescens on the tenth day after transferring Taxus sp. (RO1-M28) cell suspensions into an induction medium, further improved the production of TaxolTaxol is a registered trademark of Bristol Myers Squibb for paclitaxel. and total taxanes. Arachidonic acid (1mg/L) addition at the time of inoculation increased Taxol production by 150%. Oxidative stress… CONTINUE READING
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