Elevations of cardiac troponin I associated with myocarditis. Experimental and clinical correlates.

@article{Smith1997ElevationsOC,
  title={Elevations of cardiac troponin I associated with myocarditis. Experimental and clinical correlates.},
  author={Stanton Smith and Jack H. Ladenson and J. Wright Mason and Allan S. Jaffe},
  journal={Circulation},
  year={1997},
  volume={95 1},
  pages={163-8}
}
BACKGROUND Endomyocardial biopsy is currently the standard method used to diagnose myocarditis. However, it is invasive and has a low diagnostic yield. Because the histological diagnosis of myocarditis requires the presence of myocyte injury, we sought to determine whether measurement of cardiac troponin I (cTnI), which is a serum marker with high sensitivity and specificity for cardiac myocyte injury, could aid in the diagnosis of myocarditis. METHODS AND RESULTS To validate this approach… CONTINUE READING

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