Elevation of surfactant protein A in plasma and sputum in cigarette smokers.

  title={Elevation of surfactant protein A in plasma and sputum in cigarette smokers.},
  author={Witold Mazur and Tuula I Toljamo and Steffen Ohlmeier and Katri Vuopala and Pentti Nieminen and Hitoshi Kobayashi and Vuokko L. Kinnula},
  journal={The European respiratory journal},
  volume={38 2},
Serum surfactant protein (SP)-A has been postulated to associate with pulmonary fibrosis, but its role in cigarette smoking-related lung diseases is undefined. SP-A levels in plasma and induced sputum in nonsmokers, smokers with respiratory symptoms (cough and/or phlegm) and symptom-free smokers were assessed using a validated EIA method. A total of 474 current smokers without any diseases or medications were enrolled and followed for 2 yrs with 111 of them succeeding in stopping. Plasma SP-A… CONTINUE READING
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