Elevation of p-NR2A(S1232) by Cdk5/p35 contributes to retinal ganglion cell apoptosis in a rat experimental glaucoma model.

Abstract

Glaucoma, mainly caused by high intraocular pressure (IOP), is characterized by apoptotic death of retinal ganglion cells (RGCs). We investigated the possible involvement of cyclin-dependent kinase 5 (Cdk5) and its activator p35, which have been implicated in a variety of neurological disorders, in RGC apoptosis in a rat experimental glaucoma model… (More)
DOI: 10.1016/j.nbd.2011.04.019

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@article{Chen2011ElevationOP, title={Elevation of p-NR2A(S1232) by Cdk5/p35 contributes to retinal ganglion cell apoptosis in a rat experimental glaucoma model.}, author={Jie Chen and Yanying Miao and Xiao-Han Wang and Zhong-feng Wang}, journal={Neurobiology of disease}, year={2011}, volume={43 2}, pages={455-64} }