Elevation of oxidative free radicals in Alzheimer's disease models can be attenuated by Ginkgo biloba extract EGb 761.

@article{Smith2003ElevationOO,
  title={Elevation of oxidative free radicals in Alzheimer's disease models can be attenuated by Ginkgo biloba extract EGb 761.},
  author={J. V. Smith and Y. Luo},
  journal={Journal of Alzheimer's disease : JAD},
  year={2003},
  volume={5 4},
  pages={
          287-300
        }
}
  • J. V. Smith, Y. Luo
  • Published 2003
  • Biology, Medicine
  • Journal of Alzheimer's disease : JAD
  • The role of amyloid beta-peptide (Abeta) in the free-radical oxidative-stress model of neurotoxicity in Alzheimer's disease (AD) has received much attention recently. In this study, we have employed both in vitro and in vivo models displaying endogenous Abeta production to study the effects of Abeta on intracellular free radical levels. We employed a neuroblastoma cell line stably expressing an AD-associated double mutation, which exhibits both increased secretion and intracellular accumulation… CONTINUE READING
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