Elevation of organ resistance due to leukocyte perfusion.

  title={Elevation of organ resistance due to leukocyte perfusion.},
  author={Don W. Sutton and Geert W Schmid-Sch{\"o}nbein},
  journal={The American journal of physiology},
  volume={262 6 Pt 2},
Leukocytes are larger and considerably less deformable than erythrocytes, thereby causing a disproportionate effect on local blood flow, which despite their low concentration, may be significant at the organ level. To investigate the degree to which circulating leukocytes affect whole organ resistance, a hemodynamically isolated rat gracilis muscle was perfused in situ under well-controlled conditions. Comparison of organ pressure-flow data from vasodilated vasculature using normal… CONTINUE READING

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