Elevation of linkage disequilibrium above neutral expectations in ancestral and derived populations of Drosophila melanogaster

@inproceedings{Garud2015ElevationOL,
  title={Elevation of linkage disequilibrium above neutral expectations in ancestral and derived populations of Drosophila melanogaster},
  author={Nandita R Garud and Dmitri A. Petrov},
  year={2015}
}
The extent to which selection and demography impact patterns of genetic diversity in natural populations of Drosophila melanogaster is yet to be fully understood. We previously observed that the pattern of LD at scales of ~10 kb in the Drosophila Genetic Reference Panel (DGRP), consisting of 145 inbred strains from Raleigh, North Carolina, measured both between pairs of sites and as haplotype homozygosity, is elevated above neutral demographic expectations. Further, we demonstrated that… CONTINUE READING

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