Elevation of GRP-78 and loss of HSP-70 following photodynamic treatment of V79 cells: sensitization by nigericin.

@article{Xue1995ElevationOG,
  title={Elevation of GRP-78 and loss of HSP-70 following photodynamic treatment of V79 cells: sensitization by nigericin.},
  author={Liang-yan Xue and M. L. Agarwal and Marie E Varnes},
  journal={Photochemistry and photobiology},
  year={1995},
  volume={62 1},
  pages={135-43}
}
Chinese hamster V79 cells were treated with photodynamic therapy (PDT) sensitized by aluminum phthalocyanine (AlPc) or with the ionophore nigericin or with combinations of PDT and nigericin. We previously showed that PDT and nigericin interact synergistically in the killing of these cells; i.e. doses of PDT that kill no more than 10% of the cells in combination with nontoxic exposures to nigericin lead to a loss of clonogenicity of three to five orders of magnitude. Photodynamic therapy induces… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 11 extracted citations

Similar Papers

Loading similar papers…