Elevated serum total IgE alter the diagnostic performance of radio-immune assays for β-lactam specific antibody dosing.


BACKGROUND In vivo allergy tests and the detection of drug-specific antibodies are widely used in the diagnosis of β-lactam induced immediate-type hypersensitivity reactions. The diagnostic performance of immunoenzymatic tests for the demonstration of serum-specific IgE (IgEs) antibodies is influenced by total IgE values (IgEt). The aim of this study was to… (More)