Elevated resistin levels in chronic kidney disease are associated with decreased glomerular filtration rate and inflammation, but not with insulin resistance.

@article{Axelsson2006ElevatedRL,
  title={Elevated resistin levels in chronic kidney disease are associated with decreased glomerular filtration rate and inflammation, but not with insulin resistance.},
  author={Jonas Axelsson and Alicia Bergsten and Abdul Rashid Qureshi and Olof Heimb{\"u}rger and Peter Barany and Fredrik L{\"o}nnqvist and Bengt Lindholm and Louise Nordfors and Anders Alvestrand and Peter Stenvinkel},
  journal={Kidney international},
  year={2006},
  volume={69 3},
  pages={596-604}
}
In the present study, we explore the role of decreased renal function and a genetic polymorphism on the recently discovered protein resistin, apparently able to inhibit hepatic insulin action in mice. We also investigate possible links with inflammation and the insulin resistance present in patients with chronic kidney disease (CKD). This is a post hoc, cross-sectional study comparing 239 prevalent CKD patients with varying degrees of renal function impairment with an age- and gender-matched… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 88 extracted citations

Similar Papers

Loading similar papers…