Elevated red cell adenosine deaminase activity: a marker of disordered erythropoiesis in Diamond‐Blackfan anaemia and other haematologic diseases

@article{Glader1988ElevatedRC,
  title={Elevated red cell adenosine deaminase activity: a marker of disordered erythropoiesis in Diamond‐Blackfan anaemia and other haematologic diseases},
  author={B. Glader and Karen Backer},
  journal={British Journal of Haematology},
  year={1988},
  volume={68}
}
  • B. Glader, K. Backer
  • Published 1 February 1988
  • Medicine, Biology
  • British Journal of Haematology
Red‐cell adenosine deaminase (ADA) activity in children with Diamond‐Blackfan anaemia is significantly increased (1·91±0·90 U/g Hb) compared to that seen in transient erythroblastopenia of childhood (0·80±0·16 U/g Hb) or normal individuals (0·61±0·13 U/g). These data thus further support that measurement of this purine metabolic enzyme is useful in diagnosing the cause of pure RBC aplasia in children. Of interest, however, elevated RBC‐ADA activity also is seen in some children with acute… 
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