Elevated protein carbonyls as plasma markers of oxidative stress in acute pancreatitis.

@article{Winterbourn2003ElevatedPC,
  title={Elevated protein carbonyls as plasma markers of oxidative stress in acute pancreatitis.},
  author={Christine C Winterbourn and M. Bonham and Hendrikje Buss and Fikri M Abu-Zidan and John Albert Windsor},
  journal={Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]},
  year={2003},
  volume={3 5},
  pages={
          375-82
        }
}
BACKGROUND Experimental studies have demonstrated that protein and lipid oxidation is a feature of acute pancreatitis and that antioxidant pretreatment can ameliorate the severity of the disease. Justification for a clinical trial of antioxidant therapy requires stronger evidence for oxidative stress in patients. AIMS To determine if oxidative stress is evident in patients with acute pancreatitis on admission to hospital, if it increases after admission and if it is related to disease… CONTINUE READING
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