Elevated plasma von Willebrand factor levels in patients with active ulcerative colitis reflect endothelial perturbation due to systemic inflammation.

@article{Zezos2005ElevatedPV,
  title={Elevated plasma von Willebrand factor levels in patients with active ulcerative colitis reflect endothelial perturbation due to systemic inflammation.},
  author={Petros Zezos and Georgia Ch. Papaioannou and N. S. Nikolaidis and Themistoclis Vasiliadis and Olga I Giouleme and Nikolaos Evgenidis},
  journal={World journal of gastroenterology},
  year={2005},
  volume={11 48},
  pages={
          7639-45
        }
}
AIM To evaluate the plasma von Willebrand factor (vWF) levels in patients with ulcerative colitis (UC) and to investigate their relationship with disease activity, systemic inflammation and coagulation activation. METHODS In 46 patients with ulcerative colitis (active in 34 patients), clinical data were gathered and plasma vWF levels, markers of inflammation (ESR, CRP, and fibrinogen) and thrombin generation (TAT, F1+2, and D-dimers) were measured at baseline and after 12 wk of treatment… CONTINUE READING

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