Elevated plasma levels of the long pentraxin, pentraxin 3, in severe dengue virus infections.

@article{Mairuhu2005ElevatedPL,
  title={Elevated plasma levels of the long pentraxin, pentraxin 3, in severe dengue virus infections.},
  author={Albert T. A. Mairuhu and Giuseppe Peri and Tatty E. Setiati and Cornelis Erik Hack and Penelopie Koraka and Augustinus Soemantri and Albert D M E Osterhaus and Desiderius P. M. Brandjes and Jos W M van der Meer and Alberto Mantovani and Eric van Gorp},
  journal={Journal of medical virology},
  year={2005},
  volume={76 4},
  pages={547-52}
}
C-reactive protein is one of the most widely used indicators of the response of acute-phase proteins. The measurement of C-reactive protein in dengue, however, is clinically not useful, because of marginally elevated levels and absent association with disease severity. The prototypic long pentraxin, pentraxin 3, is an acute phase protein that is structurally related but distinct from C-reactive protein which has proven to correlate with the severity of bacterial infection in critically ill… CONTINUE READING

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