Elevated plasma homocysteine was associated with hemorrhagic and ischemic stroke, but methylenetetrahydrofolate reductase gene C677T polymorphism was a risk factor for thrombotic stroke: a Multicenter Case-Control Study in China.

@article{Li2003ElevatedPH,
  title={Elevated plasma homocysteine was associated with hemorrhagic and ischemic stroke, but methylenetetrahydrofolate reductase gene C677T polymorphism was a risk factor for thrombotic stroke: a Multicenter Case-Control Study in China.},
  author={Zhaohui Li and Li Sun and Hongye Zhang and Yu-hua Liao and Dao Wen Wang and Bingrang Zhao and Zhiming Zhu and Jizong Zhao and Ai-qun Ma and Yu Han and Yibo Wang and Yi Shi and Jue Ye and Rutai Hui},
  journal={Stroke},
  year={2003},
  volume={34 9},
  pages={2085-90}
}
BACKGROUND AND PURPOSE It is still controversial whether elevated plasma homocysteine and the C677T polymorphism of methylenetetrahydrofolate reductase (MTHFR) gene are risk factors for stroke. The aim of the present study was to investigate the association between the 2 factors and stroke in Chinese in a large case-control study. METHODS We recruited 1823 stroke patients (807 cerebral thrombosis, 513 lacunar infarction, 503 intracerebral hemorrhage) and 1832 controls. Total plasma… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 60 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 37 references

Plasma homocysteine concentration , C 677 T MTHFR genotype , and 844 ins 68 bp CBS genotype in young adults with spontaneous cervical artery dissection and athero - thrombotic

  • HS Markus, N Ali, R Swaminathan, A Sankaralingam, J Molloy, J Powell
  • STROKE
  • 2002

Similar Papers

Loading similar papers…