Elevated plasma TFPI activity causes attenuated TF-dependent thrombin generation in early onset preeclampsia.

@article{Egan2017ElevatedPT,
  title={Elevated plasma TFPI activity causes attenuated TF-dependent thrombin generation in early onset preeclampsia.},
  author={Karl Egan and Hugh O'connor and Barry Kevane and Fergal Malone and {\'A}ine Lennon and Amani Al Zadjali and Sharon Cooley and Cathy Monteith and Patricia Maguire and Paulina B. Szklanna and Seamus Allen and Naomi McCallion and Fionnuala B N{\'i} Ainle},
  journal={Thrombosis and haemostasis},
  year={2017},
  volume={117 8},
  pages={
          1549-1557
        }
}
Early onset preeclampsia (EOP) is a pregnancy-specific proinflammatory disorder that is characterised by competing thrombotic and bleeding risks. It was the aim of this study to characterise thrombin generation, a major determinant of thrombotic and bleeding risk, in order to better understand the haemostatic balance in patients with EOP. Patients with EOP… CONTINUE READING