Elevated placental estradiol: a possible etiological factor of human cryptorchidism.

@article{Hadziselimovic2000ElevatedPE,
  title={Elevated placental estradiol: a possible etiological factor of human cryptorchidism.},
  author={Faruk Hadziselimovic and Renata Geneto and Lyman R Emmons},
  journal={The Journal of urology},
  year={2000},
  volume={164 5},
  pages={1694-5}
}
PURPOSE It has been convincingly argued that the increasing incidence of reproductive abnormalities in human males may be associated with increased estrogen exposure during gestation. We documented the expression of estradiol in the syncytiotrophoblast and placenta of males born with cryptorchidism and normal genitalia, respectively. MATERIALS AND METHODS Tissue from newborn placentas was fixed in glutaraldehyde and embedded in ePON for immunohistological procedures. Cryptorchidism was… CONTINUE READING

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