Elevated peripheral cytokines characterize a subgroup of people with schizophrenia displaying poor verbal fluency and reduced Broca's area volume

@inproceedings{Fillman2016ElevatedPC,
  title={Elevated peripheral cytokines characterize a subgroup of people with schizophrenia displaying poor verbal fluency and reduced Broca's area volume},
  author={Stuart G Fillman and Thomas W Weickert and Rhoshel K. Lenroot and S. V. Catts and Jason M. Bruggemann and Vibeke S\orensen Catts and Cynthia Shannon Weickert},
  booktitle={Molecular Psychiatry},
  year={2016}
}
Previous studies on schizophrenia have detected elevated cytokines in both brain and blood, suggesting neuroinflammation may contribute to the pathophysiology in some cases. We aimed to determine the extent to which elevated peripheral cytokine messenger RNA (mRNA) expression: (1) characterizes a subgroup of people with schizophrenia and (2) shows a relationship to cognition, brain volume and/or symptoms. Forty-three outpatients with schizophrenia or schizoaffective disorder and matched healthy… CONTINUE READING
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Gene expression profiling by mRNA sequencing reveals increased expression of immune/inflammation-related genes in the hippocampus of individuals with schizophrenia

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