Elevated neutrophil function in chronic neutrophilic leukemia.

  title={Elevated neutrophil function in chronic neutrophilic leukemia.},
  author={Toshiho Ohtsuki and Yuki Katsura and Hiroaki Mizukami and Yasuhiko Matsu-ura and Fumihiko Kimura and Mutsuko Ohnishi and Norikazu Nagata and Kazuo Motoyoshi},
  journal={American journal of hematology},
  volume={41 1},
A 65-year-old man with marked leukocytosis was admitted for diagnosis and treatment. His peripheral blood leukocyte count was 37,500/microliters and the leukocytes consisted of mature neutrophil-like cells. A high neutrophil alkaline phosphatase score and a normal bone marrow cell karyotype suggested that the patient had chronic neutrophilic leukemia rather than chronic myeloid leukemia. Several neutrophil functions, such as superoxide production, nitroblue tetrazolium reduction activity, and… CONTINUE READING