Elevated microsatellite instability at selected tetranucleotide repeats does not correlate with clinicopathologic features of bladder cancer.

@article{Burger2006ElevatedMI,
  title={Elevated microsatellite instability at selected tetranucleotide repeats does not correlate with clinicopathologic features of bladder cancer.},
  author={Maximilian Burger and Sarah Julia Burger and Stefan Denzinger and Peter J. Wild and Wolf Ferdinand Wieland and Hagen J. Blaszyk and Ellen Christina Obermann and Robert Franz St{\"o}hr and Arndt Hartmann},
  journal={European urology},
  year={2006},
  volume={50 4},
  pages={770-5; discussion 776}
}
INTRODUCTION The aim of the present study was to evaluate whether elevated microsatellite instability (MSI) at selected tetranucleotide repeats (EMAST) is associated with clinicopathologic and molecular parameters in urinary bladder cancer (BC). METHODS A consecutive series of 117 nonselected urothelial BCs was studied. Microsatellite analysis and detection of loss of heterozygosity (LOH) was performed after microdissection by using 12 markers selected for sensitive detection of EMAST… CONTINUE READING