Elevated mean diffusivity in the left hemisphere superior longitudinal fasciculus in autism spectrum disorders increases with more profound language impairment.

@article{Nagae2012ElevatedMD,
  title={Elevated mean diffusivity in the left hemisphere superior longitudinal fasciculus in autism spectrum disorders increases with more profound language impairment.},
  author={L{\'i}dia Mayumi Nagae and Deborah M. Zarnow and Lisa Blaskey and John Dell and Sarah Y. Khan and Saba Qasmieh and S. E. Levy and T. P. Pradeepa Roberts},
  journal={AJNR. American journal of neuroradiology},
  year={2012},
  volume={33 9},
  pages={1720-5}
}
BACKGROUND AND PURPOSE Language impairments are observed in a subset of individuals with ASD. To examine microstructural brain white matter features associated with language ability in ASD, we measured the DTI parameters of language-related white matter tracts (SLF) as well as non-language-related white matter tracts (CST) in children with ASD/+LI and ASD/-LI) and in TD. MATERIALS AND METHODS Eighteen children with ASD/-LI (age range, 6.7-17.5 years), 17 with ASD/+LI (age range, 6.8-14.8… CONTINUE READING

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