Elevated levels of plasma angiogenic factors are associated with human lymphatic filarial infections.

@article{Bennuru2010ElevatedLO,
  title={Elevated levels of plasma angiogenic factors are associated with human lymphatic filarial infections.},
  author={Sasisekhar Bennuru and Grace A Maldarelli and Vasanthapuram Kumaraswami and Amy D Klion and Thomas B Nutman},
  journal={The American journal of tropical medicine and hygiene},
  year={2010},
  volume={83 4},
  pages={884-90}
}
Lymphatic dilatation, dysfunction, and lymphangiogenesis are hallmarks of patent lymphatic filariasis, observed even in those with subclinical microfilaremia, through processes associated, in part, by vascular endothelial growth factors (VEGFs). A panel of pro-angiogenic factors was measured in the plasma of subjects from filaria-endemic regions using multiplexed immunological assays. Compared with endemic normal control subjects, those with both subclinical microfilaremia, and those with… CONTINUE READING