Elevated levels of leukotriene C4 in bronchoalveolar lavage fluid from atopic asthmatics after endobronchial allergen challenge.

@article{Wenzel1990ElevatedLO,
  title={Elevated levels of leukotriene C4 in bronchoalveolar lavage fluid from atopic asthmatics after endobronchial allergen challenge.},
  author={Sally E Wenzel and G L Drake Larsen and Kimberly Johnston and Norbert Felix Voelkel and Jay Y. Westcott},
  journal={The American review of respiratory disease},
  year={1990},
  volume={142 1},
  pages={112-9}
}
Sulfidopeptide leukotrienes have been implicated in the pathogenesis of asthma because of their ability to induce bronchospasm, airways hyperreactivity, and increased mucus production. In the present study, the leukotrienes (LT) C4, D4, and E4 were measured in bronchoalveolar lavage fluid (BALF) before and 5 min after endobronchial allergen challenge in four subject groups: nonatopic nonasthmatic, nonatopic asthmatic, atopic nonasthmatic, and atopic asthmatic. As determined by high performance… CONTINUE READING

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