Elevated levels of decidual insulin-like growth factor binding protein-1 in cervical fluid in early and mid-pregnancy are associated with an increased risk of spontaneous preterm delivery.

@article{Rahkonen2010ElevatedLO,
  title={Elevated levels of decidual insulin-like growth factor binding protein-1 in cervical fluid in early and mid-pregnancy are associated with an increased risk of spontaneous preterm delivery.},
  author={Leena Rahkonen and E-M Rutanen and Mika Nuutila and Susanna Sainio and Terhi Saisto and Jorma Paavonen},
  journal={BJOG : an international journal of obstetrics and gynaecology},
  year={2010},
  volume={117 6},
  pages={701-10}
}
OBJECTIVE To study whether elevated levels of decidual insulin-like growth factor binding protein-1 (IGFBP-1) in the cervical fluid of unselected asymptomatic women in early or mid-pregnancy are associated with spontaneous preterm delivery (PTD). DESIGN Prospective population-based cohort study. SETTING Maternity Clinics, University Central Hospital, Helsinki, Finland. POPULATION A total of 5180 unselected pregnant women. METHODS Cervical swab samples were collected during the first and… CONTINUE READING

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