Elevated levels of N-terminal pro-opiomelanocortin peptides in fetal sheep plasma may contribute to fetal adrenal gland development and the pre-parturient cortisol surge.

@article{Saphier1993ElevatedLO,
  title={Elevated levels of N-terminal pro-opiomelanocortin peptides in fetal sheep plasma may contribute to fetal adrenal gland development and the pre-parturient cortisol surge.},
  author={P W Saphier and Bill Glynn and Russell J. Woods and Dean A. Shepherd and M K Jeacock and Philip J. Lowry},
  journal={Endocrinology},
  year={1993},
  volume={133 3},
  pages={1459-61}
}
Parturition in sheep is initiated by a rapid rise in fetal plasma cortisol. There is some controversy as to the exact nature of the drive for this pre-partum cortisol surge and it is thought that factors other than ACTH may act in concert to stimulate the development of the fetal adrenal gland. We have investigated the concentrations of ACTH and other… CONTINUE READING