Elevated levels of GABA+ in migraine detected using (1) H-MRS.

  title={Elevated levels of GABA+ in migraine detected using (1) H-MRS.},
  author={Maria-Eliza R Aguila and Jim Lagopoulos and Andrew Leaver and Trudy Rebbeck and Markus H{\"u}bscher and Patrick C. Brennan and Kathryn Margaret Refshauge},
  journal={NMR in biomedicine},
  volume={28 7},
γ-Aminobutyric acid (GABA) has been implicated in several pain conditions, yet no study has systematically evaluated GABA levels in migraine using (1) H-MRS. The accurate detection, separation and quantification of GABA in individuals with migraine could elucidate the role of this neurotransmitter in migraine pathophysiology. Such information may eventually be useful in the diagnosis and development of more effective treatments for migraine. The aims of this study were therefore to compare the… CONTINUE READING


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