Elevated levels of D-dimer and fragment 1+2 upon central venous catheter insertion and factor V Leiden predict subclavian vein thrombosis.

@article{Jansen2005ElevatedLO,
  title={Elevated levels of D-dimer and fragment 1+2 upon central venous catheter insertion and factor V Leiden predict subclavian vein thrombosis.},
  author={Flip H. Jansen and Hanneke M van der Straaten and Mark R. Roest and Fred J.L.M. Haas and Philip G. de Groot and Rob Fijnheer},
  journal={Haematologica},
  year={2005},
  volume={90 4},
  pages={
          499-504
        }
}
BACKGROUND AND OBJECTIVES Subclavian vein thrombosis is a well-recognized complication following central venous catheter insertion. We studied whether the determination of D-dimer levels, fragment 1+2 levels and factor V Leiden can identify patients at high risk of developing subclavian vein thrombosis. DESIGN AND METHODS The presence of central venous catheter associated thrombosis was analyzed in 235 patients undergoing allogeneic bone marrow transplantation, of whom 30 (13%) developed… CONTINUE READING

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