Elevated expression of prostaglandin E2 synthetic pathway in skeletal muscle of prior polio patients.

@article{Melin2014ElevatedEO,
  title={Elevated expression of prostaglandin E2 synthetic pathway in skeletal muscle of prior polio patients.},
  author={Eva O Melin and Eva Lindroos and Ingrid E Lundberg and Kristian Borg and Marina N. Korotkova},
  journal={Journal of rehabilitation medicine},
  year={2014},
  volume={46 1},
  pages={67-72}
}
OBJECTIVE The aim of this study was to investigate signs of inflammation in muscle of patients with prior polio, since the main symptoms in these patients are muscle pain, weakness and fatigue. In the context of pain and inflammation, the prostaglandin E2 pathway is of interest. Prostaglandin E2 has many biological actions and is a mediator of inflammation and pain. PATIENTS AND METHODS Skeletal muscle biopsies from 8 patients with prior polio and post-polio symptoms, presenting with pain and… CONTINUE READING
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