Elevated expression of cancer-associated proliferating cell nuclear antigen in high-grade prostatic intraepithelial neoplasia and prostate cancer.

@article{Wang2011ElevatedEO,
  title={Elevated expression of cancer-associated proliferating cell nuclear antigen in high-grade prostatic intraepithelial neoplasia and prostate cancer.},
  author={Xiaoyan Wang and Robert J. Hickey and Linda H. Malkas and Michael O Koch and Lang Li and Shaobo Zhang and George Earl Sandusky and David J. Grignon and John Nelson Eble and Liang Cheng},
  journal={The Prostate},
  year={2011},
  volume={71 7},
  pages={748-54}
}
BACKGROUND Proliferating cell nuclear antigen (PCNA) plays an important role in DNA replication and repair. The expression and potential utility of this marker in prostatic neoplasia is uncertain. With the development of this new caPCNA selective antibody, we explored the potential utility of this marker in prostate cancer. METHODS Using a traditional primary Fab2' rabbit anti-caPCNA antibody-HRP conjugated secondary anti-Fab2' antibody format, the expression of the caPCNA was analyzed in… CONTINUE READING