Elevated expression of HIF-lα in actively growing prostate tissues is associated with clinical features of benign prostatic hyperplasia

@inproceedings{Wu2016ElevatedEO,
  title={Elevated expression of HIF-lα in actively growing prostate tissues is associated with clinical features of benign prostatic hyperplasia},
  author={Fei Wu and Sentai Ding and Xin Li and Hui Wang and Shuai Liu and Haihu Wu and Dongbin Bi and Kejia Ding and Jiaju Lu},
  booktitle={Oncotarget},
  year={2016}
}
BACKGROUND Benign prostatic hyperplasia (BPH) is one of the most common diseases in middle-age or older men. Increasing evidence has shown that BPH is associated with hypoxia microenvironment. METHODS We retrospectively collected patient data and tissue samples from fetal prostates(FP), normal prostates(NP), intra-acinar of BPH, peri-acinar of BPH, prostate cancers and sarcomas of prostate. The expression of HIF-1α, as well as VEGF was visualized by immunohistochemistry and statistically… CONTINUE READING
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