Elevated expression level of long noncoding RNA MALAT-1 facilitates cell growth, migration and invasion in pancreatic cancer.

@article{Jiao2014ElevatedEL,
  title={Elevated expression level of long noncoding RNA MALAT-1 facilitates cell growth, migration and invasion in pancreatic cancer.},
  author={Feng Jiao and Hai Hu and Cuncun Yuan and Lei Wang and Weihua Jiang and Ziliang Jin and Zhen Guo and Liwei Wang},
  journal={Oncology reports},
  year={2014},
  volume={32 6},
  pages={
          2485-92
        }
}
Pancreatic cancer is one of the most aggressive solid malignancies with a dismal survival rate. Recent studies have shown that high expression levels of long noncoding RNA (lncRNA) metastasis-associated lung adenocarcinoma transcript-1 (MALAT-1) correlate with several solid tumors. However, the underlying molecular mechanisms and its clinical significance in pancreatic cancer remain to be elucidated. In the present study, our results showed that MALAT-1 expression levels were upregulated in… CONTINUE READING

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