Elevated expression and potential roles of human Sp5, a member of Sp transcription factor family, in human cancers.

Abstract

In this report, we describe the expression and function of human Sp5, a member of the Sp family of zinc finger transcription factors. Like other family members, the Sp5 protein contains a Cys2His2 zinc finger DNA binding domain at the C-terminus. Our experiments employing Gal4-Sp5 fusion proteins reveal multiple transcriptional domains, including a N… (More)

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@article{Chen2006ElevatedEA, title={Elevated expression and potential roles of human Sp5, a member of Sp transcription factor family, in human cancers.}, author={Yongxin Chen and Yingqiu Guo and Xijin Ge and Hirotaka Itoh and Akira Watanabe and Takeshi Fujiwara and Tatsuhiko Kodama and Hiroyuki Aburatani}, journal={Biochemical and biophysical research communications}, year={2006}, volume={340 3}, pages={758-66} }