Elevated concentrations of endogenous ouabain in patients with congestive heart failure.

@article{Gottlieb1992ElevatedCO,
  title={Elevated concentrations of endogenous ouabain in patients with congestive heart failure.},
  author={Stephen S Gottlieb and Artur Rogowski and Margalit Weinberg and Cathy M. Krichten and Bruce P. M. Hamilton and John M. Hamlyn},
  journal={Circulation},
  year={1992},
  volume={86 2},
  pages={420-5}
}
BACKGROUND An endogenous digitalis-like compound in mammals has long been postulated, but only recently has a substance indistinguishable from ouabain been identified in human plasma. Because of the potential significance of such a substance in patients with congestive heart failure, we sought to evaluate the pathophysiology of endogenous ouabain in these individuals. METHODS AND RESULTS Using an immunoassay, we determined plasma ouabain concentrations in 51 patients with heart failure and in… CONTINUE READING

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References

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Showing 1-10 of 35 references

Development of an immunoassay for endogenous digitalislike factor

  • DW DuCharme
  • Hypertension
  • 1991

Increased plasma levels of ouabainlike compound ( OLC ) in dialysis patients : Relationship with interdialytic volume changes ? ( abstract )

  • J Schaeffer, J Talartschik, KM Koch, AC Rogowski, P Manunta, JM Hamlyn
  • Abstracts of the Endocrine Society
  • 1990

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