Elevated circulating microRNA-122 is associated with obesity and insulin resistance in young adults.

  title={Elevated circulating microRNA-122 is associated with obesity and insulin resistance in young adults.},
  author={Rui Wang and Jie Hong and Yanan Cao and Juan Shi and Weiqiong Gu and Guang Ning and Yifei Zhang and Weiqing Wang},
  journal={European journal of endocrinology},
  volume={172 3},
OBJECTIVE MicroRNAs (miRNAs) are involved in the regulation of adiposity, but functional studies have yielded inconclusive results. Examining the associations of circulating miRNAs levels with obesity and insulin sensitivity in humans may lead to improved insights. DESIGN AND METHODS Serum samples collected from 112 obese and control subjects (50.0% men) were randomly divided and combined into four pools (28 samples in each obese or control pool). The genome-wide circulating miRNA profiles… 

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