Elevated cerebrospinal fluid levels of substance P in patients with the fibromyalgia syndrome.

@article{Russell1994ElevatedCF,
  title={Elevated cerebrospinal fluid levels of substance P in patients with the fibromyalgia syndrome.},
  author={Irwin Jon Russell and M D Orr and Bruce Littman and Gilbert Vipraio and D Alboukrek and Joel E. Michalek and Yolanda L{\'o}pez and F MacKillip},
  journal={Arthritis and rheumatism},
  year={1994},
  volume={37 11},
  pages={1593-601}
}
OBJECTIVE To measure, and seek clinical correlates with, levels of substance P (SP) in the cerebrospinal fluid (CSF) of fibromyalgia syndrome (FMS) patients. METHODS CSF from 32 FMS patients and 30 normal control subjects was tested for SP by radioimmunoassay. Clinical measures included tender point examination and standardized questionnaires. RESULTS CSF SP levels were 3-fold higher in FMS patients than in normal controls (P < 0.001), but they correlated only weakly with tenderness found… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 2 times over the past 90 days. VIEW TWEETS

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 163 extracted citations

Similar Papers

Loading similar papers…