Elevated body temperature exaggerates laryngeal chemoreflex apnea in decerebrate piglets.

Abstract

We investigated the interaction between body temperature and the duration of the laryngeal chemoreflex (LCR) in decerebrate piglets. Elevating body temperature by approximately 2 degrees C prolongs the duration of the LCR and the length of apnea associated with the reflex. This thermal prolongation seems to arise within the nucleus of the solitary tract in the brainstem, and we believe the thermal effect is mediated by enhanced GABAergic neurotransmission.

Cite this paper

@article{Xia2008ElevatedBT, title={Elevated body temperature exaggerates laryngeal chemoreflex apnea in decerebrate piglets.}, author={Luxi Xia and Tracey Damon and James C Leiter and Donald R. Bartlett}, journal={Advances in experimental medicine and biology}, year={2008}, volume={605}, pages={249-54} }