Elevated blood plasma concentrations of active ghrelin and obestatin in benign ovarian neoplasms and ovarian cancers.

@article{Markowska2009ElevatedBP,
  title={Elevated blood plasma concentrations of active ghrelin and obestatin in benign ovarian neoplasms and ovarian cancers.},
  author={Anna I. Markowska and Alicja Zi{\'o}łkowska and Karolina Jaszczyńska-Nowinka and Radosław Mądry and Ludwik K. Malendowicz},
  journal={European journal of gynaecological oncology},
  year={2009},
  volume={30 5},
  pages={518-22}
}
Both ghrelin and obestatin are derived from preproghrelin by post-translational processing. The two peptides are secreted into the blood but circulating levels of these peptides have not been assessed in women with ovarian tumours. Therefore, the purpose of this study was to evaluate peripheral blood concentrations of active and total ghrelin and obestatin in patients with benign ovarian tumours and those with ovarian cancer. The studies were conducted on 22 patients operated due to benign… CONTINUE READING
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