Elevated blood levels of inflammation-related proteins are associated with an attention problem at age 24 mo in extremely preterm infants

@article{OShea2014ElevatedBL,
  title={Elevated blood levels of inflammation-related proteins are associated with an attention problem at age 24 mo in extremely preterm infants},
  author={Thomas Michael O’Shea and Robert M. Joseph and Karl K. C. Kuban and Elizabeth N. Allred and Janice Ware and Taryn Coster and Raina Nakova Fichorova and Olaf Dammann and Alan Leviton},
  journal={Pediatric Research},
  year={2014},
  volume={75},
  pages={781-787}
}
Background:Extremely preterm birth is associated with subsequent behavioral problems. We hypothesized that perinatal systemic inflammation, a risk factor for cerebral white matter injury and cognitive impairment, is associated with behavior problems observed at 2 y.Methods:In a cohort of 600 children born before 28 wk gestation, we measured 25 inflammation-related proteins in blood collected on postnatal days 1, 7, and 14, and identified behavior problems using parent responses to the Child… CONTINUE READING
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