Elevated arterial cyclic AMP levels during the development of spontaneous hypertension in rats.

@article{Chatelain1985ElevatedAC,
  title={Elevated arterial cyclic AMP levels during the development of spontaneous hypertension in rats.},
  author={R. Chatelain and B. Dardik and R. D. Robson},
  journal={European journal of pharmacology},
  year={1985},
  volume={112 2},
  pages={
          271-5
        }
}
Vascular cyclic AMP alterations were studied during the initiation of vascular hypertrophy and hyperplasia in spontaneously hypertensive rats (SHR). The onset of hypertension at 6 weeks of age coexisted with a three-fold elevation in the aortic content and concentration of cyclic AMP, whereas aortic DNA and protein contents were identical to those of WKY controls. A similar cyclic AMP elevation was present in 12-week-old SHR when vascular hypertrophy and hyperplasia were already established… Expand
7 Citations
Aortic cyclic AMP levels in hypertensive rats.
Unaltered caffeine-induced relaxation in the aorta of stroke-prone spontaneously hypertensive rats (SHRSP).

References

SHOWING 1-10 OF 11 REFERENCES
Aberrations of cyclic nucleotide metabolism in the hearts and vessels of hypertensive rats.
Age-related changes in vascular responsiveness to cyclic nucleotides and contractile agonists.
  • M. Cohen, B. Berkowitz
  • Chemistry, Medicine
  • The Journal of pharmacology and experimental therapeutics
  • 1974
Protein measurement with the Folin phenol reagent.
Role of cyclic nucleotides in growth control.
...
1
2
...