Elevated Tribbles homolog 2-specific antibody levels in narcolepsy patients.

@article{CvetkovicLopes2010ElevatedTH,
  title={Elevated Tribbles homolog 2-specific antibody levels in narcolepsy patients.},
  author={Vesna Cvetkovic-Lopes and Laurence Bayer and St{\'e}phane Dorsaz and St{\'e}phanie Maret and Sylvain Pradervand and Yves Dauvilliers and Michel Lecendreux and G H Lammers and Claire E. H. M. Donjacour and Renaud A. Du Pasquier and Corinne Pfister and Brice Petit and H. F. Hor and Michel M{\"u}hlethaler and Mehdi Tafti},
  journal={The Journal of clinical investigation},
  year={2010},
  volume={120 3},
  pages={713-9}
}
Narcolepsy is a sleep disorder characterized by excessive daytime sleepiness and attacks of muscle atonia triggered by strong emotions (cataplexy). Narcolepsy is caused by hypocretin (orexin) deficiency, paralleled by a dramatic loss in hypothalamic hypocretin-producing neurons. It is believed that narcolepsy is an autoimmune disorder, although definitive proof of this, such as the presence of autoantibodies, is still lacking. We engineered a transgenic mouse model to identify peptides enriched… CONTINUE READING

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ELISA analysis showed that sera from narcolepsy patients with cataplexy had higher Trib2-specific antibody titers compared with either normal controls or patients with idiopathic hypersomnia , multiple sclerosis , or other inflammatory neurological disorders .
ELISA analysis showed that sera from narcolepsy patients with cataplexy had higher Trib2-specific antibody titers compared with either normal controls or patients with idiopathic hypersomnia , multiple sclerosis , or other inflammatory neurological disorders .
ELISA analysis showed that sera from narcolepsy patients with cataplexy had higher Trib2-specific antibody titers compared with either normal controls or patients with idiopathic hypersomnia , multiple sclerosis , or other inflammatory neurological disorders .
Narcolepsy is a sleep disorder characterized by excessive daytime sleepiness and attacks of muscle atonia triggered by strong emotions ( cataplexy ) .
ELISA analysis showed that sera from narcolepsy patients with cataplexy had higher Trib2-specific antibody titers compared with either normal controls or patients with idiopathic hypersomnia , multiple sclerosis , or other inflammatory neurological disorders .
Narcolepsy is a sleep disorder characterized by excessive daytime sleepiness and attacks of muscle atonia triggered by strong emotions ( cataplexy ) .
ELISA analysis showed that sera from narcolepsy patients with cataplexy had higher Trib2-specific antibody titers compared with either normal controls or patients with idiopathic hypersomnia , multiple sclerosis , or other inflammatory neurological disorders .
Narcolepsy is a sleep disorder characterized by excessive daytime sleepiness and attacks of muscle atonia triggered by strong emotions ( cataplexy ) .
Narcolepsy is a sleep disorder characterized by excessive daytime sleepiness and attacks of muscle atonia triggered by strong emotions ( cataplexy ) .
ELISA analysis showed that sera from narcolepsy patients with cataplexy had higher Trib2-specific antibody titers compared with either normal controls or patients with idiopathic hypersomnia , multiple sclerosis , or other inflammatory neurological disorders .
ELISA analysis showed that sera from narcolepsy patients with cataplexy had higher Trib2-specific antibody titers compared with either normal controls or patients with idiopathic hypersomnia , multiple sclerosis , or other inflammatory neurological disorders .
ELISA analysis showed that sera from narcolepsy patients with cataplexy had higher Trib2-specific antibody titers compared with either normal controls or patients with idiopathic hypersomnia , multiple sclerosis , or other inflammatory neurological disorders .
ELISA analysis showed that sera from narcolepsy patients with cataplexy had higher Trib2-specific antibody titers compared with either normal controls or patients with idiopathic hypersomnia , multiple sclerosis , or other inflammatory neurological disorders .
ELISA analysis showed that sera from narcolepsy patients with cataplexy had higher Trib2-specific antibody titers compared with either normal controls or patients with idiopathic hypersomnia , multiple sclerosis , or other inflammatory neurological disorders .
ELISA analysis showed that sera from narcolepsy patients with cataplexy had higher Trib2-specific antibody titers compared with either normal controls or patients with idiopathic hypersomnia , multiple sclerosis , or other inflammatory neurological disorders .
ELISA analysis showed that sera from narcolepsy patients with cataplexy had higher Trib2-specific antibody titers compared with either normal controls or patients with idiopathic hypersomnia , multiple sclerosis , or other inflammatory neurological disorders .
Narcolepsy is a sleep disorder characterized by excessive daytime sleepiness and attacks of muscle atonia triggered by strong emotions ( cataplexy ) .
ELISA analysis showed that sera from narcolepsy patients with cataplexy had higher Trib2-specific antibody titers compared with either normal controls or patients with idiopathic hypersomnia , multiple sclerosis , or other inflammatory neurological disorders .
ELISA analysis showed that sera from narcolepsy patients with cataplexy had higher Trib2-specific antibody titers compared with either normal controls or patients with idiopathic hypersomnia , multiple sclerosis , or other inflammatory neurological disorders .
ELISA analysis showed that sera from narcolepsy patients with cataplexy had higher Trib2-specific antibody titers compared with either normal controls or patients with idiopathic hypersomnia , multiple sclerosis , or other inflammatory neurological disorders .
Narcolepsy is a sleep disorder characterized by excessive daytime sleepiness and attacks of muscle atonia triggered by strong emotions ( cataplexy ) .
Narcolepsy is a sleep disorder characterized by excessive daytime sleepiness and attacks of muscle atonia triggered by strong emotions ( cataplexy ) .
Narcolepsy is a sleep disorder characterized by excessive daytime sleepiness and attacks of muscle atonia triggered by strong emotions ( cataplexy ) .
Narcolepsy is a sleep disorder characterized by excessive daytime sleepiness and attacks of muscle atonia triggered by strong emotions ( cataplexy ) .
ELISA analysis showed that sera from narcolepsy patients with cataplexy had higher Trib2-specific antibody titers compared with either normal controls or patients with idiopathic hypersomnia , multiple sclerosis , or other inflammatory neurological disorders .
ELISA analysis showed that sera from narcolepsy patients with cataplexy had higher Trib2-specific antibody titers compared with either normal controls or patients with idiopathic hypersomnia , multiple sclerosis , or other inflammatory neurological disorders .
ELISA analysis showed that sera from narcolepsy patients with cataplexy had higher Trib2-specific antibody titers compared with either normal controls or patients with idiopathic hypersomnia , multiple sclerosis , or other inflammatory neurological disorders .
ELISA analysis showed that sera from narcolepsy patients with cataplexy had higher Trib2-specific antibody titers compared with either normal controls or patients with idiopathic hypersomnia , multiple sclerosis , or other inflammatory neurological disorders .
ELISA analysis showed that sera from narcolepsy patients with cataplexy had higher Trib2-specific antibody titers compared with either normal controls or patients with idiopathic hypersomnia , multiple sclerosis , or other inflammatory neurological disorders .
ELISA analysis showed that sera from narcolepsy patients with cataplexy had higher Trib2-specific antibody titers compared with either normal controls or patients with idiopathic hypersomnia , multiple sclerosis , or other inflammatory neurological disorders .
Narcolepsy is a sleep disorder characterized by excessive daytime sleepiness and attacks of muscle atonia triggered by strong emotions ( cataplexy ) .
Narcolepsy is a sleep disorder characterized by excessive daytime sleepiness and attacks of muscle atonia triggered by strong emotions ( cataplexy ) .
Narcolepsy is a sleep disorder characterized by excessive daytime sleepiness and attacks of muscle atonia triggered by strong emotions ( cataplexy ) .
Narcolepsy is a sleep disorder characterized by excessive daytime sleepiness and attacks of muscle atonia triggered by strong emotions ( cataplexy ) .
Narcolepsy is a sleep disorder characterized by excessive daytime sleepiness and attacks of muscle atonia triggered by strong emotions ( cataplexy ) .
Narcolepsy is a sleep disorder characterized by excessive daytime sleepiness and attacks of muscle atonia triggered by strong emotions ( cataplexy ) .
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