Elevated Th17 cells are accompanied by FoxP3+ Treg cells decrease in patients with lupus nephritis

@article{Xing2010ElevatedTC,
  title={Elevated Th17 cells are accompanied by FoxP3+ Treg cells decrease in patients with lupus nephritis},
  author={Qian Xing and Bin Wang and Houheng Su and Jiajia Cui and Jinghua Li},
  journal={Rheumatology International},
  year={2010},
  volume={32},
  pages={949-958}
}
To investigate the variations of T-helper 17 (Th17) and regulatory T (Treg) cells in patients with lupus nephritis (LN), a total of 60 systemic lupus erythematosus patients and 28 healthy controls (HCs) were enrolled. The frequency of Th17 cells and Treg cells in peripheral blood mononuclear cells (PBMCs) was evaluated by flow cytometric analysis. The serum concentrations of interleukin-17 (IL-17) and transforming growth factor-beta 1 (TGF-β1) were measured by enzyme-linked immunosorbent assay… CONTINUE READING
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