Elevated Nitric Oxide/Peroxynitrite Mechanism for the Common Etiology of Multiple Chemical Sensitivity, Chronic Fatigue Syndrome, and Posttraumatic Stress Disorder

@article{Pall2001ElevatedNO,
  title={Elevated Nitric Oxide/Peroxynitrite Mechanism for the Common Etiology of Multiple Chemical Sensitivity, Chronic Fatigue Syndrome, and Posttraumatic Stress Disorder},
  author={M. Pall and J. Satterlee},
  journal={Annals of the New York Academy of Sciences},
  year={2001},
  volume={933}
}
Various types of evidence implicate nitric oxide and an oxidant, possibly peroxynitrite, in MCS and chemical intolerance (CI). The positive feedback loops proposed earlier for CFS may explain the chronic nature of MCS (CI) as well as several of its other reported properties. These observations raise the possibility that this proposed elevated nitric oxide/peroxynitrite mechanism may be the mechanism of a new disease paradigm, answering the question raised by Miller earlier: "Are we on the… Expand
84 Citations
Role of Polymorphisms of Inducible Nitric Oxide Synthase and Endothelial Nitric Oxide Synthase in Idiopathic Environmental Intolerances
  • 16
  • PDF
Multiple Chemical Sensitivity : Towards the End of Controversy
  • 2
  • PDF
Specific correlations between muscle oxidative stress and chronic fatigue syndrome: a working hypothesis
  • 46
NMDA sensitization and stimulation by peroxynitrite, nitric oxide, and organic solvents as the mechanism of chemical sensitivity in multiple chemical sensitivity
  • M. Pall
  • Chemistry, Medicine
  • FASEB journal : official publication of the Federation of American Societies for Experimental Biology
  • 2002
  • 65
  • PDF
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 48 REFERENCES
Elevated, sustained peroxynitrite levels as the cause of chronic fatigue syndrome.
  • M. Pall
  • Chemistry, Medicine
  • Medical hypotheses
  • 2000
  • 110
Role of nitric oxide in the regulation of myocardial function.
  • 176
Nitric oxide in the kidney: synthesis, localization, and function.
  • S. Bachmann, P. Mundel
  • Medicine
  • American journal of kidney diseases : the official journal of the National Kidney Foundation
  • 1994
  • 281
Multiple chemical sensitivity: potential role for neural sensitization.
  • B. Sorg
  • Psychology, Medicine
  • Critical reviews in neurobiology
  • 1999
  • 64
Role of nitric oxide in hematosuppression and benzene-induced toxicity.
  • 22
...
1
2
3
4
5
...