Elevated MMP-8 and decreased myeloperoxidase concentrations associate significantly with the risk for peripheral atherosclerosis disease and abdominal aortic aneurysm.

@article{PradhanPalikhe2010ElevatedMA,
  title={Elevated MMP-8 and decreased myeloperoxidase concentrations associate significantly with the risk for peripheral atherosclerosis disease and abdominal aortic aneurysm.},
  author={Pratikshya Pradhan-Palikhe and Pirkka Vikatmaa and Taina K Lajunen and Anil Palikhe and Mauri J. A. Lep{\"a}ntalo and Taina I Tervahartiala and Tuula Salo and Pekka Saikku and Maija Leinonen and Pirkko J Pussinen and Timo Sorsa},
  journal={Scandinavian journal of immunology},
  year={2010},
  volume={72 2},
  pages={150-7}
}
Matrix metalloproteinases are responsible for degradation and remodelling of extracellular matrix and exert important roles in initiation and progression of inflammatory diseases. We aimed to examine the role of Matrix metalloproteinases (MMPs) and their regulators in degenerative arterial diseases. Serum samples were collected from patients with arterial disease (n = 126), who underwent surgery because of symptomatic aorto-occlusive disease (AOD, n = 18), carotid artery stenosis (n = 67) or… CONTINUE READING