Elevated Levels of Chemokines in Esophageal Mucosa of Patients With Reflux Esophagitis

  title={Elevated Levels of Chemokines in Esophageal Mucosa of Patients With Reflux Esophagitis},
  author={Hajime Isomoto and Aiping Wang and Yohei Mizuta and Yuko Akazawa and Kazuo Ohba and Katsuhisa Omagari and Masanobu Miyazaki and Kunihiko Murase and Tomayoshi Hayashi and Kenichiro Inoue and Ikuo Murata and Shigeru Kohno},
  journal={American Journal of Gastroenterology},
OBJECTIVE:Chemokines play a key role in the pathogenesis of various inflammatory conditions. However, there is little information on their profile in reflux esophagitis (RE). We sought to study esophageal mucosa levels of chemokines in RE.METHODS:A total of 32 outpatients with RE and 13 normal controls were studied. Endoscopic severity of RE was classified according to the Los Angeles grading system. Paired biopsy specimens were taken from the esophagus 3 cm above the gastroesophageal junction… CONTINUE READING
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Acid reflux is a poor predictor of esophageal mucosal injury

  • B Avidan, A Sonnenberg, T. Schnell
  • Gastronetrology
  • 2000

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