Elevated IL-8 levels in the drainage vein of resectable Dukes' C colorectal cancer indicate high risk for developing hepatic metastasis.

@article{Haraguchi2002ElevatedIL,
  title={Elevated IL-8 levels in the drainage vein of resectable Dukes' C colorectal cancer indicate high risk for developing hepatic metastasis.},
  author={Masashi Haraguchi and Ko Komuta and Arifumi Akashi and Sumihiro Matsuzaki and Junichiro Furui and Takashi Kanematsu},
  journal={Oncology reports},
  year={2002},
  volume={9 1},
  pages={159-65}
}
To investigate the relationship between tumor angiogenesis and hematogenous metastasis in colorectal cancer, an immunohistochemical analysis using antibody against factor VIII was carried out on archival specimens of 35 primary tumors. In addition, we also evaluated the levels of vascular endothelial growth factor (VEGF) and interleukin-8 (IL-8), by an enzyme-linked immunosorbent assay (ELISA), in tumor specimens and the serum in the drainage venous blood. The levels of VEGF showed no… CONTINUE READING