Elevated IL-5 and IL-13 responses to egg proteins predate the introduction of egg in solid foods in infants with eczema.

@article{Metcalfe2016ElevatedIA,
  title={Elevated IL-5 and IL-13 responses to egg proteins predate the introduction of egg in solid foods in infants with eczema.},
  author={Jessica Metcalfe and Nina D'vaz and Maria Makrides and Michael S Gold and Patrick John Quinn and Christina E. West and Richard K S Loh and Susan L. Prescott and Debra J Palmer},
  journal={Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology},
  year={2016},
  volume={46 2},
  pages={308-16}
}
BACKGROUND Egg allergy is a leading cause of food allergy in young infants; however, little is known about early allergen-specific T-cell responses which predate the presentation of egg allergy, and if these are altered by early egg exposure. OBJECTIVE To investigate the early T-cell responses to multiple egg proteins in relation to patterns of egg exposure and subsequent IgE-mediated egg allergy. METHODS Egg-specific T-cell cytokine responses (IL-5, IL-13, IL-10, IFNγ and TNFα) to… CONTINUE READING
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